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Startups allow technologists and scientists to take risks and change plans in a way that would be frowned upon in a big company. Having said that, big companies will play a key role in certain areas and in partnerships with little companies. Each has its strengths.

Vinod Khosla

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Vinod Khosla
Age: 69
Born: 1955
Born: January 28
Businessman
Businessperson
National Capital Region of Delhi
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Scientists
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Companies
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Scientist
Technologists
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Bigs
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More quotes by Vinod Khosla

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I generally disagree with most of the very high margin opportunities. Why? Because it's a business strategy tradeoff: the lower the margin you take, the faster you grow.
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There's no doubt in my mind over the next 25 years how we drive, how we build our houses, how we fly, how we build our buildings, will all change.
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We humans think linearly but tech trends are exponential.
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Seeking an acquisition from the start is more than just bad advice for an entrepreneur. For the entrepreneur it leads to short term tactical decisions rather than company-building decisions and in my view often reduces the probability of success.
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Entrepreneurs have the flexibility and the ability to do things that large companies simply cannot. Could a large company pull off a trick like Amyris, going from anti-malaria medicine to next-generation fuel?
Vinod Khosla
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Certain food-based biofuels like biodiesel have always been a bad idea. Others like corn ethanol have served a useful purpose and essentially are obsoleting themselves.
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Screw up often but screw up ahead of everybody else, and than learn as much, and than use it to make subsequent investments.
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Maybe some percentage that’s substantially larger than 95 percent of VCs add zero value. I would bet that 70-80 percent add negative value to a startup in their advising.
Vinod Khosla
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Future is not extrapolation of past
Vinod Khosla
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I don’t mind failing, but if I succeed it better be worth succeeding for.
Vinod Khosla
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Success comes to those that dare to dream dreams and are foolish enough to try and make them come true.
Vinod Khosla
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Doctors can be replaced by software – 80% of them can. I’d much rather have a good machine learning system diagnose my disease than the median or average doctor.
Vinod Khosla
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Will biofuel usage require land? Absolutely, but we think the ability to use winter cover crops, degraded land, as well as using sources such as organic waste, sewage, and forest waste means that actual land usage will be limited. Just these sources can replace most of our imported oil by 2030 without touching new land.
Vinod Khosla
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I do not know what got me interested in technology. What was very clear to me very early on was that I was not interested in religion and that naturally increased my curiosity about science and technology, and I fundamentally believe the two are conflicting.
Vinod Khosla
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Communication always changes society, and society was always organized around communication channels. Two hundred years ago it was mostly rivers. It was sea-lanes and mountain passes. The Internet is another form of communication and commerce. And society organizes around the channels.
Vinod Khosla
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Where most entrepreneurs fail is on the things they don't know they don't know.
Vinod Khosla
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Climate deniers are clearly the fringe group and need to see a proctologist to find their heads.
Vinod Khosla
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I'm a fiscal hawk. I vote against all taxes, but I do believe the environment, and climate change, is a bigger issue than fiscal deficits are as a risk to the nation.
Vinod Khosla
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You need a degree of foolishness to cause disruptive change in healthcare. Dare to dream.
Vinod Khosla
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Your cellphone has 10 sensors, and your car has 400. But your body has none - that's going to change.
Vinod Khosla