Sometimes guessing is the best you can do. In the real world, we guess all the time and it serves us well.

Humans are very good at making algorithms work eventually.

When you walk around, your vision system is processing a whole bunch of signals in milliseconds and judging that a visual object is a wall, or an imminent cliff, or a car heading towards you. This might be disturbing to a lot of people, but some of those guesses are errors.

The brain has a good error rate. But, the point is, you can function with that error rate. Animals do a lot of guesswork.

There is no such thing as zero uncertainty.