The weird part is actually, there were so many exceptionally talented people there [ on MADtv]. But it was a disaster. I don't think I enjoyed any of it, really. I had a different sensibility.

I was like, I can't believe I get to be in a scene with Meryl Streep [in Florence Foster Jenkins]! And then I was like, but why do I have to play Chopin? It's already going to be intimidating.

There's also these moments when you're like, oh, I really want to do different things. Not instead of this show [The Big Bang Theory]. It's just a hunger to do something else, too.

I came in [MADtv] kind of late in the season. Some of the producers didn't want me but the network did. It was all (messed up) from the beginning.

There's no real escape from the work, but in some ways, if you're as obsessive as I am, it's a sweet little thing we've figured out. You bring your work home and you work 24 hours a day, but it's good.

I wanted to come to Chicago. I also wanted to do Saturday Night Live. And then I got to a place where I didn't want to do those things anymore.For the sketch comedy thing, I got cast on MADtv, and that will kill any man's desire to do comedy.

It's amazing to watch somebody who is kind of this sleazy, degenerate lothario, sex-crazed guy become sort of a romantic, settled-down man about to have a baby.

It's not really about confidence. It's just something that isn't really in the vocabulary of what goes on at work. The writers write and the actors act.

I always honestly dreamed of coming to Second City in Chicago, although I've never even been there to see a show. But I did a ton of sketch comedy at the Second City in LA, which (at the time, in a different location) wasn't really a theater, it was just a space where you took some classes.

Well, I think that everybody is kind of a nerd at heart.

I actually struggled through teaching myself to cook because I'm completely ignorant in the kitchen. So I did really macho things like trying to make my own curry. Really hardcore stuff.

Actually, when I was young, I believe I met Nicolas Cage. I think I was probably eight, and I remember seeing him at somebody's house - it was an event and he happened to be there. People would ask me if I was his son, because I looked like him at that point, so I do remember feeling some connection and just wanting to say, like, 'Papa!'

I was young. I was 23 or 24. I just wasn't a fan of the politics of campaigning - of going into that environment and competing and trying to get into the good graces of the writers.

Meryl Streep is so brilliant is because she is so human, and aware as a performer.