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In YC's case, the number one cause of early death for startups is cofounder blowups.

Sam Altman

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Sam Altman
Age: 39
Born: 1985
Born: April 22
Entrepreneur
Chicago
Illinois
Samuel H. Altman
Samuel Altman
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More quotes by Sam Altman

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If it takes more than a sentence to explain what you are doing, it's almost always a sign that what you are doing is too complicated.
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I believe in fighting with investors to reduce the amount of equity they get and then being as generous as you possibly can with employees.
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... but actually it sucks to have a lot of employees, and you should be proud of how few employees you have.
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You can basically change everything in a startup but the market.
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The natural state of a start-up is to die most start-ups require multiple miracles in their early days to escape this fate.
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The track record for founders that don't already know each other is really bad.
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Most good founders that I know at any given time have a set of small overarching goals for the company that everybody in the company knows.
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So always keep momentum, it's this prime directive for managing a startup.
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Growth and momentum are what a startup lives on and you always have to focus on maintaining these.
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Developing a personal connection with anyone you're trying to do a big deal with is really important.
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You can have a startup and one other thing, you can have a family, but you probably can't have many other things.
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The way to have a company that executes well is you have to execute well yourself.
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You cannot create a market that doesn't want to exist.
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If it works out, you're going to be working on this for 10 years.
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You need to figure out what the 2 or 3 most important things are, and then just do those.
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Unfortunately the trick to great execution is to say no a lot.
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Whatever the founder cares about, whatever the founders think are the key goals, that's going to be what the whole company focusses on.
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Great execution towards a terrible idea will get you nowhere.
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Momentum and growth are the lifeblood of startups. This is probably in the top three secrets of executing well.
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Founders need to figure out what the message of the company is going to be.
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