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The frontal cortex doesn't even fully develop until age 25, which is wild!

Robert M. Sapolsky

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Robert M. Sapolsky
Fully
Develop
Age
Doesn
Even
Frontal
Cortex
Wild

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As long as experiencing your optimal level of good stress doesn't damage others, it's hard to objectively define where normal enjoyment of stimulation becomes adrenaline junkiehood.
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The regulation of genes is often more interesting than the genes themselves, and it's the environment that regulates genes.
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Most people who do a lot of exercise, particularly in the form of competitive athletics, have unneurotic, extraverted, optimistic personalities to begin with. (Marathon runners are exceptions to this.)
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Genes are important for understanding our behavior. Incredibly important - after all, they code for every protein pertinent to brain function, endocrinology, etc.
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I love science, and it pains me to think that so many are terrified of the subject or feel that choosing science means you cannot also choose compassion, or the arts, or be awed by nature. Science is not meant to cure us of mystery, but to reinvent and reinvigorate it.
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Importantly, rather than promoting aggression, testosterone promotes whatever is needed to maintain status when challenged.
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Get it wrong, and we call it a cult. Get it right, in the right time and the right place, and maybe, for the next few millennia, people won't have to go to work on your birthday.
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But often, it's easier to resist temptation with distraction, or to be so inculcated in doing the right thing that it's automatic, outside the frontal cortex's portfolio - Then it isn't the harder thing, it's the only thing you can do.
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We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.
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...I might continue to believe that there is no god even if it were proved that there is. A religious friend of mine once remarked that the concept of god is useful, because you can berate god during the bad times. But it is clear to me that I don't need to believe there is a god in order to berate him.
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If you care about your longevity and health, be a socially affiliated baboon who is better than high-ranking ones at walking away from provocations.
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If I had to define a major depression in a single sentence, I would describe it as a genetic/neurochemical disorder requiring a strong environmental trigger whose characteristic manifestation is an inability to appreciate sunsets.
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What happened in the milliseconds before a behavior to cause it? That's in the neurobiological realm.
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How much you groom somebody else is more important than who grooms you.
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We are just another primate but a very confused, malleable one.
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The gigantic challenge is the magnitude of the individual differences in the optimal set point for good stress. For one person, it's doing something risky with your bishop in a chess game for someone else, it's becoming a mercenary in Yemen.
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The less it is possible that something can be, the more it must be.
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