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If I had to define a major depression in a single sentence, I would describe it as a genetic/neurochemical disorder requiring a strong environmental trigger whose characteristic manifestation is an inability to appreciate sunsets.

Robert M. Sapolsky

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Robert M. Sapolsky
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More quotes by Robert M. Sapolsky

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Get it wrong, and we call it a cult. Get it right, in the right time and the right place, and maybe, for the next few millennia, people won't have to go to work on your birthday.
Robert M. Sapolsky
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I love science, and it pains me to think that so many are terrified of the subject or feel that choosing science means you cannot also choose compassion, or the arts, or be awed by nature. Science is not meant to cure us of mystery, but to reinvent and reinvigorate it.
Robert M. Sapolsky
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What happened in the milliseconds before a behavior to cause it? That's in the neurobiological realm.
Robert M. Sapolsky
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Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.
Robert M. Sapolsky
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Only humans invent moralizing gods who monitor our behavior.
Robert M. Sapolsky
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Stress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.
Robert M. Sapolsky
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The gigantic challenge is the magnitude of the individual differences in the optimal set point for good stress. For one person, it's doing something risky with your bishop in a chess game for someone else, it's becoming a mercenary in Yemen.
Robert M. Sapolsky
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We're getting along so well I trust you so much for this one second that I'm going to let you yank on me.
Robert M. Sapolsky
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The less it is possible that something can be, the more it must be.
Robert M. Sapolsky
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What does the frontal cortex do? Gratification postponement, executive function, long-term planning, and impulse control. Basically, it makes you do the harder thing.
Robert M. Sapolsky
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Give lab rats oxytocin and, according to that meme, they get better at talking about their feelings and sing like Joan Baez.
Robert M. Sapolsky
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Until you appreciate something crucial - It is incredibly easy to manipulate us as to who counts as an Us, who as a Them.
Robert M. Sapolsky
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How much you groom somebody else is more important than who grooms you.
Robert M. Sapolsky
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It's great to have a buff frontal cortex to do that harder thing - for example, help a person in need rather buy some useless, shiny gee-gaw.
Robert M. Sapolsky
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The frontal cortex doesn't even fully develop until age 25, which is wild!
Robert M. Sapolsky
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An open mind is a prerequisite to an open heart.
Robert M. Sapolsky
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We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.
Robert M. Sapolsky
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If a rat is a good model for your emotional life, you're in big trouble.
Robert M. Sapolsky
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Most people who do a lot of exercise, particularly in the form of competitive athletics, have unneurotic, extraverted, optimistic personalities to begin with. (Marathon runners are exceptions to this.)
Robert M. Sapolsky
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We’ve evolved to be smart enough to make ourselves sick.
Robert M. Sapolsky