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If I had to define a major depression in a single sentence, I would describe it as a genetic/neurochemical disorder requiring a strong environmental trigger whose characteristic manifestation is an inability to appreciate sunsets.

Robert M. Sapolsky

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Robert M. Sapolsky
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More quotes by Robert M. Sapolsky

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We’ve evolved to be smart enough to make ourselves sick.
Robert M. Sapolsky
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The most important point of [Susan] Fiske's work is that it provides a taxonomy for our differing feelings about different Thems - sometimes fear, sometimes ridicule, sometimes contemptuous pity, sometimes savagery.
Robert M. Sapolsky
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The frontal cortex doesn't even fully develop until age 25, which is wild!
Robert M. Sapolsky
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I had never planned to become a savanna baboon when I grew up instead, I had always assumed I would become a mountain gorilla.
Robert M. Sapolsky
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...I might continue to believe that there is no god even if it were proved that there is. A religious friend of mine once remarked that the concept of god is useful, because you can berate god during the bad times. But it is clear to me that I don't need to believe there is a god in order to berate him.
Robert M. Sapolsky
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It's probably even the case that if you stoked up some Buddhist monks with tons of testosterone, they'd become wildly competitive as to who can do the most acts of random kindness.
Robert M. Sapolsky
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Perhaps most excitingly, we are uncovering the brain basis of our behaviors - normal, abnormal and in-between. We are mapping a neurobiology of what makes us us.
Robert M. Sapolsky
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Naturally, things are more complicated - those groovy, pro-social effects of oxytocin apply to how we interact with in-group members.
Robert M. Sapolsky
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The less it is possible that something can be, the more it must be.
Robert M. Sapolsky
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Genes are rarely about inevitability, especially when it comes to humans, the brain, or behavior. They're about vulnerability, propensities, tendencies.
Robert M. Sapolsky
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We're getting along so well I trust you so much for this one second that I'm going to let you yank on me.
Robert M. Sapolsky
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Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.
Robert M. Sapolsky
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Oxytocin is lauded for how it promotes warmth, generosity, social bonding, cooperation, trust, and compassion.
Robert M. Sapolsky
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Only humans invent moralizing gods who monitor our behavior.
Robert M. Sapolsky
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But often, it's easier to resist temptation with distraction, or to be so inculcated in doing the right thing that it's automatic, outside the frontal cortex's portfolio - Then it isn't the harder thing, it's the only thing you can do.
Robert M. Sapolsky
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Give lab rats oxytocin and, according to that meme, they get better at talking about their feelings and sing like Joan Baez.
Robert M. Sapolsky
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The gigantic challenge is the magnitude of the individual differences in the optimal set point for good stress. For one person, it's doing something risky with your bishop in a chess game for someone else, it's becoming a mercenary in Yemen.
Robert M. Sapolsky
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It's great to have a buff frontal cortex to do that harder thing - for example, help a person in need rather buy some useless, shiny gee-gaw.
Robert M. Sapolsky
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What happened during the minutes before? That's the realm of sensory stimuli of the nervous system.
Robert M. Sapolsky
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Get it wrong, and we call it a cult. Get it right, in the right time and the right place, and maybe, for the next few millennia, people won't have to go to work on your birthday.
Robert M. Sapolsky