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If I had to define a major depression in a single sentence, I would describe it as a genetic/neurochemical disorder requiring a strong environmental trigger whose characteristic manifestation is an inability to appreciate sunsets.

Robert M. Sapolsky

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Robert M. Sapolsky
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More quotes by Robert M. Sapolsky

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The gigantic challenge is the magnitude of the individual differences in the optimal set point for good stress. For one person, it's doing something risky with your bishop in a chess game for someone else, it's becoming a mercenary in Yemen.
Robert M. Sapolsky
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Genes are important for understanding our behavior. Incredibly important - after all, they code for every protein pertinent to brain function, endocrinology, etc.
Robert M. Sapolsky
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Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.
Robert M. Sapolsky
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It's probably even the case that if you stoked up some Buddhist monks with tons of testosterone, they'd become wildly competitive as to who can do the most acts of random kindness.
Robert M. Sapolsky
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As long as experiencing your optimal level of good stress doesn't damage others, it's hard to objectively define where normal enjoyment of stimulation becomes adrenaline junkiehood.
Robert M. Sapolsky
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I love science, and it pains me to think that so many are terrified of the subject or feel that choosing science means you cannot also choose compassion, or the arts, or be awed by nature. Science is not meant to cure us of mystery, but to reinvent and reinvigorate it.
Robert M. Sapolsky
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Naturally, things are more complicated - those groovy, pro-social effects of oxytocin apply to how we interact with in-group members.
Robert M. Sapolsky
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We live well enough to have the luxury to get ourselves sick with purely social, psychological stress.
Robert M. Sapolsky
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Perhaps most excitingly, we are uncovering the brain basis of our behaviors - normal, abnormal and in-between. We are mapping a neurobiology of what makes us us.
Robert M. Sapolsky
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We're getting along so well I trust you so much for this one second that I'm going to let you yank on me.
Robert M. Sapolsky
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Give lab rats oxytocin and, according to that meme, they get better at talking about their feelings and sing like Joan Baez.
Robert M. Sapolsky
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We’ve evolved to be smart enough to make ourselves sick.
Robert M. Sapolsky
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How much you groom somebody else is more important than who grooms you.
Robert M. Sapolsky
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Importantly, rather than promoting aggression, testosterone promotes whatever is needed to maintain status when challenged.
Robert M. Sapolsky
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Most people who do a lot of exercise, particularly in the form of competitive athletics, have unneurotic, extraverted, optimistic personalities to begin with. (Marathon runners are exceptions to this.)
Robert M. Sapolsky
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Oxytocin is lauded for how it promotes warmth, generosity, social bonding, cooperation, trust, and compassion.
Robert M. Sapolsky
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What happened in the milliseconds before a behavior to cause it? That's in the neurobiological realm.
Robert M. Sapolsky
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...I might continue to believe that there is no god even if it were proved that there is. A religious friend of mine once remarked that the concept of god is useful, because you can berate god during the bad times. But it is clear to me that I don't need to believe there is a god in order to berate him.
Robert M. Sapolsky
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If you care about your longevity and health, be a socially affiliated baboon who is better than high-ranking ones at walking away from provocations.
Robert M. Sapolsky
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An open mind is a prerequisite to an open heart.
Robert M. Sapolsky