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If I had to define a major depression in a single sentence, I would describe it as a genetic/neurochemical disorder requiring a strong environmental trigger whose characteristic manifestation is an inability to appreciate sunsets.

Robert M. Sapolsky

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Robert M. Sapolsky
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More quotes by Robert M. Sapolsky

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The regulation of genes is often more interesting than the genes themselves, and it's the environment that regulates genes.
Robert M. Sapolsky
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We are just another primate but a very confused, malleable one.
Robert M. Sapolsky
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Most people who do a lot of exercise, particularly in the form of competitive athletics, have unneurotic, extraverted, optimistic personalities to begin with. (Marathon runners are exceptions to this.)
Robert M. Sapolsky
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An open mind is a prerequisite to an open heart.
Robert M. Sapolsky
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Genes are rarely about inevitability, especially when it comes to humans, the brain, or behavior. They're about vulnerability, propensities, tendencies.
Robert M. Sapolsky
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We live well enough to have the luxury to get ourselves sick with purely social, psychological stress.
Robert M. Sapolsky
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It's probably even the case that if you stoked up some Buddhist monks with tons of testosterone, they'd become wildly competitive as to who can do the most acts of random kindness.
Robert M. Sapolsky
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If a rat is a good model for your emotional life, you're in big trouble.
Robert M. Sapolsky
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As long as experiencing your optimal level of good stress doesn't damage others, it's hard to objectively define where normal enjoyment of stimulation becomes adrenaline junkiehood.
Robert M. Sapolsky
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The frontal cortex is an incredibly interesting part of the brain - ours is proportionately bigger and/or more complex than in any other species.
Robert M. Sapolsky
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It's great to have a buff frontal cortex to do that harder thing - for example, help a person in need rather buy some useless, shiny gee-gaw.
Robert M. Sapolsky
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...I might continue to believe that there is no god even if it were proved that there is. A religious friend of mine once remarked that the concept of god is useful, because you can berate god during the bad times. But it is clear to me that I don't need to believe there is a god in order to berate him.
Robert M. Sapolsky
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The frontal cortex doesn't even fully develop until age 25, which is wild!
Robert M. Sapolsky
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I had never planned to become a savanna baboon when I grew up instead, I had always assumed I would become a mountain gorilla.
Robert M. Sapolsky
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Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.
Robert M. Sapolsky
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Naturally, things are more complicated - those groovy, pro-social effects of oxytocin apply to how we interact with in-group members.
Robert M. Sapolsky
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We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.
Robert M. Sapolsky
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Oxytocin is lauded for how it promotes warmth, generosity, social bonding, cooperation, trust, and compassion.
Robert M. Sapolsky
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Perhaps most excitingly, we are uncovering the brain basis of our behaviors - normal, abnormal and in-between. We are mapping a neurobiology of what makes us us.
Robert M. Sapolsky
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If you care about your longevity and health, be a socially affiliated baboon who is better than high-ranking ones at walking away from provocations.
Robert M. Sapolsky