Two truths are all too often overshadowed in today's political discourse: Public service is a most honorable pursuit, and so is bipartisanship.

When history calls, history calls.

What motivated me to dedicate myself to public service for nearly two-thirds of my life was the chance to produce results for those people who entrusted me to be their voice and their champion.

Indeed, we must foster cost-saving competition. And that means joining the marketplace of other industrialized countries - not just for the manufacturers who sell drugs, but for consumers as well.

Most breast cancer-related deaths can be prevented through simple and painless preventive measures. A late diagnosis can result in more serious, long-term consequences.

The American spirit is stronger than stone and mortar, tougher than steel and glass, and more enduring than any pain or suffering that can be inflicted on our national conscience.

What is the purpose of public service? It's to solve problems for the people you represent and certainly in the United States Senate, thinking about your state and thinking about your country as well.

I have worked for three decades as a staunch advocate of building a big tent party that includes both pro-choice and pro-life Republicans.

Hopefully, 21 years later, Judge Roberts possesses an openness with respect to issues of gender-based wage discrimination.

I have been immeasurably honored to serve the people of Maine for nearly 40 years in public office and for the past 17 years in the United States Senate. It was incredibly difficult to decide that I would not seek a fourth term in the Senate.

What happens is that, you know, on Mondays, at least in the Senate, you know, Monday night wed have what youd call a bed-check vote. Just to get, you know, the machinery of the Senate up and running so they can start the committee process on Tuesday morning, things go. By Thursday, you know, jet fumes, the smell of jet fumes.

Ive never backed down from a fight and I relish a good debate.

Unfortunately, money in politics is an insidious thing - and a loophole in our campaign finance system was taken advantage of with money going to existing or new 527 groups with the sole purpose of influencing the election.

We recognized in 1996 that, with progress in the field of genetics accelerating at a breathtaking pace, we need to ensure that advances in treatment and prevention of disease do not constitute a new basis for discrimination.

At an unprecedented time with the worst attack ever on our soil, our President displayed extraordinary determination, leadership and resolve when history was thrust upon him and the United States.