Dr. Cox mentors the rookie doctors with a spoonful of dirt and then a cup of sugar. I see him as an archetypal descendent of two of my favorite curmudgeonly characters: Lou Grant and Louie De Palma.

TV tends to look for the living equivalents of squeaky-clean Kens and Barbies, but with my dial I'm more like Ken's dirty old uncle.

Turns out, Down syndrome is the most common genetic disorder, occurring once in every 800 births, and no one really knows why it happens. It just does.

I'm very proud of 'Platoon,' but at the end of it I was done. I was done.

I wanted to be Red Barber, Mel Allen or Howard Cosell. I loved their personalities and all of their sounds.

I would love to have a photographic memory. It would come in handy with the rants I'm given on Scrubs... often on short notice!

The learning curve on soaps is through the roof because it's a three-camera setup. There's a master and then there's two singles. And the great thing about soaps, and soap actors will tell you, is that when you get your line wrong, they don't re-shoot it. They just cut to the person listening.

My son, Max, was born the day Princess Di died.

If you watch 'E.T.' and say that there are holes in the story because this alien lands, then don't go to the movie! It drives me insane.

I'm just really proud of 'Dead Head Fred.'

I am a father. My son's name is Max and my daughter's name is Billie Grace. Twelve years ago Max was born with Down Syndrome. His journey has been complicated by infantile seizures, sleep apnea, dietary challenges and now, puberty!

I like to be in waiting rooms with people as they're auditioning, because their terror calms me.

I'm a homebody. If I'm not working I'm with my family being a dad.

I just can't afford to get bored, because if you've been blessed with a generous imagination, which a lot of actors have, to be engaged, to be stimulated, is to liberate your imagination.