There's a grand-canyon sized gulf between explanation and experience.

For some reason, that I can’t really explain, at the beginning of Radiolab, it always felt like life or death. Even though it was just a radio show. Even though no one was listening. And I am not quite sure why… but it may have to do with that radical uncertainty you feel when you are trying to work without a template.

I have a weird sense that people ten years younger than me don't own a radio, or maybe they own a radio, but they don't call it a radio.

Get comfortable with the idea that you won’t know what’s good until it’s already happened.