When I was young my Father used to tell me that the two most worthwhile pursuits in life were the pursuit of truth and of beauty and I believe that Alfred Nobel must have felt much the same when he gave these prizes for literature and the sciences.

I was married to Margaret Joan Howe in 1940. Although not a scientist herself she has contributed more to my work than anyone else by providing a peaceful and happy home.

And indeed this theme has been at the centre of all my research since 1943, both because of its intrinsic fascination and my conviction that a knowledge of sequences could contribute much to our understanding of living matter.

Until 1943 I received no stipend. I was able to support myself as my mother was the daughter of a relatively wealthy cotton manufacturer.

Influenced by him, and probably even more so by my brother Theodore a year older than me, I soon became interested in biology and developed a respect for the importance of science and the scientific method.

I and my colleagues here have been engaged in the pursuit of knowledge.

Initially I had intended to study medicine, but before going to University I had decided that I would be better suited to a career in which I could concentrate my activities and interests more on a single goal than appeared to be possible in my father's profession.

Scientific research is one of the most exciting and rewarding of occupations.