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Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.

Francis Crick

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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
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Synthesis
Science
Gene
Action
Protein
Problem
Probability
Whole
Closely
Biology
Genes
Central

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There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
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You can do reverse engineering, but you can’t do reverse hacking.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome' graduate students hardly believe they can make a discovery.
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This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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The major credit I think Jim and I deserve is for selecting the right problem and sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold.
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Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
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What could be more foolish than to base one's entire view of life on ideas that, however plausible at the time, now appear to be quite erroneous? And what would be more important than to find our true place in the universe by removing one by one these unfortunate vestiges of earlier beliefs?
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Jim and I hit it off immediately, partly because our interests were astonishingly similar and partly, I suspect, because a certain youthful arrogance, a ruthlessness, an impatience with sloppy thinking can naturally to both of us.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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Evolution is cleverer than you are.
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A busy life is a wasted life.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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You’re nothing but a pack of neurons.
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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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