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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Ideas
Sequence
Mutations
Studies
Mutation
Produced
Alterations
Final
Detailed
Finals
Discussed
Proof
Obtained
Type
Protein
Study
Acid
Amino
More quotes by Francis Crick
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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You can do reverse engineering, but you can’t do reverse hacking.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.
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Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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Christianity may be OK between consenting adults in private but should not be taught to young children.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
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A man who is right every time is not likely to do very much.
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Since I essentially knew nothing, I had an almost completely free choice.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research.
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There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
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It is notoriously difficult to define the word living.
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If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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A theory should not attempt to explain all the facts, because some of the facts are wrong
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A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
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God is a hacker, not an engineer
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
Francis Crick