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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Opposed
Triplet
Code
Biochemical
Indeed
Indirect
Method
Genetic
Evidence
Mentioned
Direct
Earlier
Methods
Shown
More quotes by Francis Crick
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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It is notoriously difficult to define the word living.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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You’re nothing but a pack of neurons.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
Francis Crick
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis Crick
What could be more foolish than to base one's entire view of life on ideas that, however plausible at the time, now appear to be quite erroneous? And what would be more important than to find our true place in the universe by removing one by one these unfortunate vestiges of earlier beliefs?
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Since I essentially knew nothing, I had an almost completely free choice.
Francis Crick
Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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Christianity may be OK between consenting adults in private but should not be taught to young children.
Francis Crick
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
Francis Crick
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.
Francis Crick
This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.
Francis Crick
God is a hacker, not an engineer
Francis Crick
Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
Francis Crick
We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
Francis Crick
Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
Francis Crick
A man who is right every time is not likely to do very much.
Francis Crick