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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Less
Lows
Deductions
Nature
Across
Genetic
Come
However
Occasionally
Would
General
Nonsense
Number
Conclusion
Numbers
Code
Since
Appear
Triplets
Rather
Secure
Triplet
More quotes by Francis Crick
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome' graduate students hardly believe they can make a discovery.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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You’re nothing but a pack of neurons.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research.
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Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
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The major credit I think Jim and I deserve is for selecting the right problem and sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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I think she [Rosalind Franklin] was a good experimentalist but certainly not of the first rank. She was simply not in the same class as Eigen or Bragg or Pauling, nor was she as good as Dorothy Hodgkin. She did not even select DNA to study. It was given to her. Her theoretical crystallography was very average.
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A man who is right every time is not likely to do very much.
Francis Crick
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick
If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
Francis Crick
Christianity may be OK between consenting adults in private but should not be taught to young children.
Francis Crick
Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
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A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
Francis Crick
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.
Francis Crick
