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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Example
Readings
Shall
Incorrect
Start
Addition
Reading
Obtain
Three
Sets
Place
Correct
Triplets
Two
Message
Grouping
Right
Messages
Triplet
More quotes by Francis Crick
In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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It is notoriously difficult to define the word living.
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Evolution is cleverer than you are.
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Since I essentially knew nothing, I had an almost completely free choice.
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Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
Francis Crick
You can do reverse engineering, but you can’t do reverse hacking.
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What could be more foolish than to base one's entire view of life on ideas that, however plausible at the time, now appear to be quite erroneous? And what would be more important than to find our true place in the universe by removing one by one these unfortunate vestiges of earlier beliefs?
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The major credit I think Jim and I deserve is for selecting the right problem and sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold.
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Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.
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Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick
Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
Francis Crick
You’re nothing but a pack of neurons.
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A busy life is a wasted life.
Francis Crick
I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
Francis Crick
God is a hacker, not an engineer
Francis Crick
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
Francis Crick