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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Two
Message
Grouping
Right
Messages
Triplet
Example
Readings
Shall
Incorrect
Start
Addition
Reading
Obtain
Three
Sets
Place
Correct
Triplets
More quotes by Francis Crick
A busy life is a wasted life.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome' graduate students hardly believe they can make a discovery.
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You’re nothing but a pack of neurons.
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Evolution is cleverer than you are.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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Since I essentially knew nothing, I had an almost completely free choice.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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Jim and I hit it off immediately, partly because our interests were astonishingly similar and partly, I suspect, because a certain youthful arrogance, a ruthlessness, an impatience with sloppy thinking can naturally to both of us.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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A man who is right every time is not likely to do very much.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
Francis Crick
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick
A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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