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If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Inactive
Triple
Added
Double
Combination
Form
Poly
Helix
More quotes by Francis Crick
You’re nothing but a pack of neurons.
Francis Crick
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.
Francis Crick
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
Francis Crick
Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
Francis Crick
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis Crick
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
Francis Crick
We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
Francis Crick
Jim and I hit it off immediately, partly because our interests were astonishingly similar and partly, I suspect, because a certain youthful arrogance, a ruthlessness, an impatience with sloppy thinking can naturally to both of us.
Francis Crick
You can do reverse engineering, but you can’t do reverse hacking.
Francis Crick
Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.
Francis Crick
Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
Francis Crick
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome' graduate students hardly believe they can make a discovery.
Francis Crick
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
Francis Crick
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
Francis Crick
It is notoriously difficult to define the word living.
Francis Crick
Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
Francis Crick
The major credit I think Jim and I deserve is for selecting the right problem and sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold.
Francis Crick
Since I essentially knew nothing, I had an almost completely free choice.
Francis Crick
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick
A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
Francis Crick
