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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
Francis Crick
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Francis Crick
Age: 88 †
Born: 1916
Born: June 8
Died: 2004
Died: July 28
Biochemist
Biologist
Geneticist
Molecular Biologist
Neuroscientist
Physicist
Scientist
University Teacher
Francis Harry Compton Crick
Francis H.C. Crick
Level
Levels
Almost
Sketchy
Understanding
Engineered
Science
Molecular
Without
Molecules
Life
Aspects
Aspect
More quotes by Francis Crick
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
Francis Crick
God is a hacker, not an engineer
Francis Crick
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
Francis Crick
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
Francis Crick
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
Francis Crick
Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.
Francis Crick
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
Francis Crick
Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
Francis Crick
It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
Francis Crick
Jim and I hit it off immediately, partly because our interests were astonishingly similar and partly, I suspect, because a certain youthful arrogance, a ruthlessness, an impatience with sloppy thinking can naturally to both of us.
Francis Crick
A busy life is a wasted life.
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If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
Francis Crick
It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
Francis Crick
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
Francis Crick
Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
Francis Crick
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
Francis Crick
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.
Francis Crick
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
Francis Crick
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
Francis Crick
